An Organ-On-Chip (OOC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems, a type of artificial organ. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing. Organ-On-Chip technology not only incorporates multiple cell types but also involves engineering aspects, such as the guided spatial confinement of cells or the incorporation of sensors and microfluidic channels.
The primary focus of Organ-On-Chip technology is the re-creation of three key aspects of human physiology: the multicellular vascular or epithelial interfaces of organs (for example, blood vessel networks, lung and gut), which function as barriers in tissues; the tissue-level organization of parenchymal cells (for example, liver, heart, skeletal muscle and tumours), which are responsible for the key functional properties of an organ; and the systematic interaction of multiple organs (for example, drug absorption, distribution, metabolism and elimination involving the gut, circulation, liver and kidney).
In addition, the Blood-Brain Barrier is definitely more complex than a simple wall, controlling the passage of most solute that enters or leaves the brain. To address how this molecular sieve affects neural activity, some researchers have simulated the interaction between blood vessels and brain tissue on a series of interconnected "organ chips" when connected through this Blood-Brain Barrier (BBB) model. Endothelial cells, pericytes, astrocytes and neurons alter their gene expression. These technologies will achieve even more rapid development and application.
This report contains market size and forecasts of Human Organs-on-Chips in global, including the following market information:
Global Human Organs-on-Chips Market Revenue, 2017-2022, 2023-2028, ($ millions)
Global Human Organs-on-Chips Market Sales, 2017-2022, 2023-2028, (K Units)
Global top five Human Organs-on-Chips companies in 2021 (%)
The global Human Organs-on-Chips market was valued at 69 million in 2021 and is projected to reach US$ 154.4 million by 2028, at a CAGR of 12.2% during the forecast period 2022-2028.
The U.S. Market is Estimated at $ Million in 2021, While China is Forecast to Reach $ Million by 2028.
Brain-on-a-chip Segment to Reach $ Million by 2028, with a % CAGR in next six years.
The global key manufacturers of Human Organs-on-Chips include Emulate, TissUse, Hesperos, CN Bio Innovations, Tara Biosystems, Draper Laboratory, Mimetas, Nortis and Micronit Microtechnologies B.V., etc. In 2021, the global top five players have a share approximately % in terms of revenue.
MARKET MONITOR GLOBAL, INC (MMG) has surveyed the Human Organs-on-Chips manufacturers, suppliers, distributors and industry experts on this industry, involving the sales, revenue, demand, price change, product type, recent development and plan, industry trends, drivers, challenges, obstacles, and potential risks.
Total Market by Segment:
Global Human Organs-on-Chips Market, by Type, 2017-2022, 2023-2028 ($ Millions) & (K Units)
Global Human Organs-on-Chips Market Segment Percentages, by Type, 2021 (%)
Brain-on-a-chip
Liver-on-a-chip
Kidney-on-a-chip
Lung-on-a-chip
Heart-on-a-chip
Intestine-on-a-chip
Vessel-on-a-chip
Other Organs
Global Human Organs-on-Chips Market, by End User, 2017-2022, 2023-2028 ($ Millions) & (K Units)
Global Human Organs-on-Chips Market Segment Percentages, by End User, 2021 (%)
Pharmaceutical & Biotechnology Companies
Academic & Research Institutes
Cosmetics Industry
Others
Global Human Organs-on-Chips Market, By Region and Country, 2017-2022, 2023-2028 ($ Millions) & (K Units)
Global Human Organs-on-Chips Market Segment Percentages, By Region and Country, 2021 (%)
North America
US
Canada
Mexico
Europe
Germany
France
U.K.
Italy
Russia
Nordic Countries
Benelux
Rest of Europe
Asia
China
Japan
South Korea
Southeast Asia
India
Rest of Asia
South America
Brazil
Argentina
Rest of South America
Middle East & Africa
Turkey
Israel
Saudi Arabia
UAE
Rest of Middle East & Africa
Competitor Analysis
The report also provides analysis of leading market participants including:
Key companies Human Organs-on-Chips revenues in global market, 2017-2022 (Estimated), ($ millions)
Key companies Human Organs-on-Chips revenues share in global market, 2021 (%)
Key companies Human Organs-on-Chips sales in global market, 2017-2022 (Estimated), (K Units)
Key companies Human Organs-on-Chips sales share in global market, 2021 (%)
Further, the report presents profiles of competitors in the market, key players include:
Emulate
TissUse
Hesperos
CN Bio Innovations
Tara Biosystems
Draper Laboratory
Mimetas
Nortis
Micronit Microtechnologies B.V.
Kirkstall
Cherry Biotech SAS
Else Kooi Laboratory